JPH0325423B2 - - Google Patents
Info
- Publication number
- JPH0325423B2 JPH0325423B2 JP1053598A JP5359889A JPH0325423B2 JP H0325423 B2 JPH0325423 B2 JP H0325423B2 JP 1053598 A JP1053598 A JP 1053598A JP 5359889 A JP5359889 A JP 5359889A JP H0325423 B2 JPH0325423 B2 JP H0325423B2
- Authority
- JP
- Japan
- Prior art keywords
- reaction
- methyl
- benzoylindole
- benzoylindolin
- mol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12698 | 1979-02-16 | ||
| US06/012,698 US4221716A (en) | 1979-02-16 | 1979-02-16 | Intermediate and process for the preparation of 7-acylindolin-2-ones |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16395179A Division JPS55111464A (en) | 1979-02-16 | 1979-12-17 | Manufacture of 77acylindolinee22one |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01265074A JPH01265074A (ja) | 1989-10-23 |
| JPH0325423B2 true JPH0325423B2 (en]) | 1991-04-05 |
Family
ID=21756265
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16395179A Granted JPS55111464A (en) | 1979-02-16 | 1979-12-17 | Manufacture of 77acylindolinee22one |
| JP1053598A Granted JPH01265074A (ja) | 1979-02-16 | 1989-03-06 | 新規な７―アシルインドール誘導体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16395179A Granted JPS55111464A (en) | 1979-02-16 | 1979-12-17 | Manufacture of 77acylindolinee22one |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4221716A (en]) |
| JP (2) | JPS55111464A (en]) |
| KR (1) | KR840001211B1 (en]) |
| AT (2) | AT375914B (en]) |
| AU (2) | AU538598B2 (en]) |
| BE (1) | BE881632A (en]) |
| CA (1) | CA1128529A (en]) |
| CH (1) | CH648828A5 (en]) |
| DE (1) | DE3005709A1 (en]) |
| DK (1) | DK157850C (en]) |
| ES (2) | ES488622A0 (en]) |
| FI (1) | FI75805C (en]) |
| FR (1) | FR2449083A1 (en]) |
| GB (2) | GB2042541B (en]) |
| IE (1) | IE49384B1 (en]) |
| IL (1) | IL59143A (en]) |
| IT (1) | IT1128362B (en]) |
| MX (1) | MX6151E (en]) |
| NL (1) | NL190283C (en]) |
| NO (2) | NO154837C (en]) |
| NZ (1) | NZ192886A (en]) |
| PH (1) | PH15317A (en]) |
| SE (3) | SE447824B (en]) |
| ZA (1) | ZA80889B (en]) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4016580A (en) * | 1975-04-21 | 1977-04-05 | Polaroid Corporation | Folding viewfinding and flash mounting assembly |
| IN163263B (en]) * | 1984-02-07 | 1988-08-27 | Pfizer | |
| US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
| US4690943A (en) * | 1984-09-19 | 1987-09-01 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| CH687764A5 (de) * | 1992-07-02 | 1997-02-14 | Lonza Ag Gampel Wallis Geschof | Verfahren zur Herstellung von 7-Acylindolen. |
| JP2004529110A (ja) | 2001-03-06 | 2004-09-24 | アストラゼネカ アクチボラグ | 脈管損傷活性を有するインドール誘導体 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3597503A (en) * | 1967-12-06 | 1971-08-03 | Hooker Chemical Corp | Cyclic phosphoroamidates and process for making same |
| US3975521A (en) * | 1969-06-30 | 1976-08-17 | Dow Corning Corporation | Prostate carcinoma treatment |
| NL90149C (en]) * | 1972-05-17 | |||
| US3897451A (en) * | 1973-04-27 | 1975-07-29 | Univ Ohio State Res Found | Synthesis of oxindoles from anilines and intermediates therein |
| US3975531A (en) * | 1973-10-02 | 1976-08-17 | A. H. Robins Company, Incorporated | 4-(5- And 7-)benzoylindolin-2-ones and pharmaceutical uses thereof |
| CH577461A5 (en]) * | 1975-08-13 | 1976-07-15 | Robins Co Inc A H | |
| AT339294B (de) * | 1975-12-22 | 1977-10-10 | Robins Co Inc A H | Verfahren zur herstellung von 4-(5- oder 7-)-benzoylindolin-2-onen |
-
1979
- 1979-02-16 US US06/012,698 patent/US4221716A/en not_active Expired - Lifetime
- 1979-12-17 JP JP16395179A patent/JPS55111464A/ja active Granted
-
1980
- 1980-01-16 IL IL59143A patent/IL59143A/xx unknown
- 1980-01-23 AU AU54873/80A patent/AU538598B2/en not_active Expired
- 1980-02-07 PH PH23614A patent/PH15317A/en unknown
- 1980-02-07 IE IE234/80A patent/IE49384B1/en not_active IP Right Cessation
- 1980-02-08 SE SE8001009A patent/SE447824B/sv not_active IP Right Cessation
- 1980-02-08 BE BE0/199332A patent/BE881632A/fr not_active IP Right Cessation
- 1980-02-08 GB GB8004314A patent/GB2042541B/en not_active Expired
- 1980-02-08 GB GB8212431A patent/GB2098208B/en not_active Expired
- 1980-02-13 MX MX808645U patent/MX6151E/es unknown
- 1980-02-14 AT AT0080080A patent/AT375914B/de not_active IP Right Cessation
- 1980-02-14 NO NO800399A patent/NO154837C/no unknown
- 1980-02-15 FR FR8003417A patent/FR2449083A1/fr active Granted
- 1980-02-15 NL NLAANVRAGE8000968,A patent/NL190283C/xx not_active IP Right Cessation
- 1980-02-15 ES ES488622A patent/ES488622A0/es active Granted
- 1980-02-15 IT IT67232/80A patent/IT1128362B/it active
- 1980-02-15 DE DE19803005709 patent/DE3005709A1/de active Granted
- 1980-02-15 CA CA345,708A patent/CA1128529A/en not_active Expired
- 1980-02-15 NZ NZ192886A patent/NZ192886A/xx unknown
- 1980-02-15 ZA ZA00800889A patent/ZA80889B/xx unknown
- 1980-02-15 CH CH1273/80A patent/CH648828A5/fr not_active IP Right Cessation
- 1980-02-15 DK DK067380A patent/DK157850C/da not_active IP Right Cessation
- 1980-02-15 KR KR1019800000617A patent/KR840001211B1/ko not_active Expired
- 1980-02-15 FI FI800464A patent/FI75805C/fi not_active IP Right Cessation
- 1980-05-26 ES ES491847A patent/ES8106703A1/es not_active Expired
-
1983
- 1983-08-08 AT AT0286983A patent/AT380235B/de not_active IP Right Cessation
-
1984
- 1984-06-12 AU AU29309/84A patent/AU564500B2/en not_active Expired
- 1984-10-30 SE SE8405429A patent/SE451720B/sv not_active IP Right Cessation
- 1984-10-30 SE SE8405430A patent/SE8405430L/xx unknown
-
1986
- 1986-04-08 NO NO86861360A patent/NO166365C/no unknown
-
1989
- 1989-03-06 JP JP1053598A patent/JPH01265074A/ja active Granted
Also Published As
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